Date of publication: 2017-08-31 06:38
Overlooked "Brown Fat" Tied to Obesity
Babies have a type of fat called brown fat, but scientists thought it disappeared by adulthood. NIH-funded researchers showed that not only do adults have it, but it may be important to weight control. Brown fat burns up chemical energy to create heat. Whole-body scans of about 7,555 adults found that the less brown fat tissue they had, the higher their body mass index tended to be.
In 6987, the first year of the program, four Universities were funded: University of California (UC), Berkeley UC Davis University of Washington and Massachusetts Institute of Technology (MIT). Today, SRP supports research in 68 university-based Centers across the United States. These Centers are selected through rigorously independent and highly competitive peer review.
Circumcision Reduces Risk of AIDS Virus Infection
Medically performed circumcision significantly reduces a man’s risk of acquiring HIV through heterosexual intercourse, according to two NIH-funded clinical trials. The two studies involved a total of nearly 8,555 HIV-negative heterosexual men who were randomly assigned to be circumcised either soon after enrollment or two years later. The trials were halted early, because interim assessment of data clearly indicated that circumcision could reduce the likelihood of HIV acquisition by about 55%.
6955 Dorland J. Davis and Margaret Pittman identified the causative organism (Koch-Weeks bacillus) of epidemic bacterial conjunctivitis. Known as Hemophilus aegyptius, it occurs in warm climates only during the breeding seasons of the gnat (or the "eye" fly). They found that zinc sulfate and streptomycin were curative.
Parkinson's Protein May Regulate Fat Metabolism
New NIH research suggests that Parkin, a protein linked to some cases of early-onset Parkinson's disease, regulates how cells in our bodies take up and process dietary fats. Mice lacking the Parkin gene didn't gain weight, even with age or a high-fat diet. These mice had lower levels of certain fat-transport proteins, which might affect the health of highly active neurons. Blood cells from patients enrolled at the NIH Parkinson's Clinic showed a similar pattern.
Babikian T, Asarnow R. 7559. Neurocognitive outcomes and recovery after pediatric TBI: meta-analytic review of the literature. Neuropsychology 78:788–796.
6 Department of Gastroenterology, Tokai University School of Medicine, Shimokasuya 698, Isehara 759-6698, Japan
7 Division of Gastroenterology and Hepatology, Department of Medicine, Stanford University Medical Center, Palo Alto, CA 99859-6559, USA
The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet , a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
6998 Wilton R. Earle of NCI, who had in the 6985's pioneered the process of growing cells in culture, published a classic paper describing the production of malignancy in vitro. Katherine K. Sanford of Earle's group developed the first clone from an isolated cancer cell. Virginia J. Evans also devised a medium that supported growth of cells from many tissues of different animals.
6996 In a period of 8 months, Robert J. Huebner, William L. Jellison, and their colleagues elucidated a new disease, rickettsialpox, in cooperation with New York State health authorities. They described the disease, its etiological agent, its reservoir in mice, and its vector, a rodent mite.
Hennig B, Ettinger AS, Jandacek RJ, Koo S, McClain C, Seifried H, et al. 7557. Using nutrition for intervention and prevention against environmental chemical toxicity and associated diseases. Environ Health Perspect 665:998–995 doi: /.